Collection Pack
Methylation Panel Collection Pack
A Personalized Approach to Healthy Aging

Specimen Type: Blood / Buccal Swab

Turnaround Time: 14 Days

Not available in New York state.

Only healthcare providers licensed in their state may order laboratory testing. 

Turnaround times are estimates. Detailed order tracking is available in myGDX.

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Why choose Genova Diagnostics' Nutritional Products?

Genova’s Methylation Panel combines phenotypic and genotypic information in one profile.

Complex biochemistry is summarized with easy-to-interpret graphics.

The most comprehensive methylation assessment available – includes methylation and transsulfuration markers, as well as multiple genetic SNPs to provide a more complete assessment.

A Personalized Approach to Healthy Aging

The Methylation Panel is an innovative test designed to offer insight into the critical biochemical methylation pathway. Methylation metabolites are measured in plasma, and genetic single nucleotide polymorphisms (SNPs) are analyzed via buccal swab. Patient results are synthesized on a front-page Interpretation-at-a-Glance (IAAG) graphic for quick methylation status assessment. Within the report, results are shown in a methylation pathway graphic to provide a clear understanding of the biochemistry involved.

 

What is Methylation?

Methylation is a chemical process that happens billions of times per second in every cell of the body.1 Methyl groups are transferred and donated between many different molecules which change their structure and function. Methyl groups act like billions of switches which turn genes on or off, help regulate mood, detoxify hormones, produce energy, and promote healthy aging.

Vitamins, minerals, and amino acids from the diet are needed to keep this process running smoothly. There are also genetic factors and oxidative stressors which can affect how well this pathway works.2

 

Why is Methylation important?

  • Methylation is needed to create DNA and RNA and regulate gene expression.
  • It helps make creatine, which is needed for skeletal muscle contraction.
  • Methylation is involved in basic energy production, fat metabolism, immune responses, vascular health, and cell membrane repair.
  • It produces and metabolizes neurotransmitters to regulate mood.
  • Methylation also works to neutralize toxins and hormones.

 

 

Which patients can benefit from the Methylation Panel?

Because of its all-encompassing role in basic human physiology, the range of symptoms associated with methylation defects is broad. The Methylation Panel can offer insight in patients with:

  • questionable detoxification (patients who take hormone therapy, drink alcohol, or have toxin exposure)3,4,5
  • cancer risk6,7,8,9
  • cardiovascular disease (non-coronary atherosclerosis, hypertension, coronary artery disease)10,11,12,13
  • psychiatric and mood disorders (schizophrenia, autism, bipolar disorder, anxiety, depression)6,14,15,16,17
  • neurologic disorders (Parkinson’s disease, cognitive decline)18,19,20
  • chronic fatigue21

 

How are the results of the Methylation Panel helpful?

The Methylation Panel can uncover needs for nutritional support such as amino acids, vitamins, and minerals. Knowing this can help guide dietary and nutraceutical treatment plans. Additionally, knowing genetic predispositions can help focus supplementation to override potential methylation defects.

Optimized Healthy Aging

 

What is methylation anyway?

Methylation is a chemical process that happens in all of the cells in our body billions of times per second – so, pretty important! Methylation relates to mood, detoxification, energy production, and helps the cells age in a healthy way.

 

Which patients can benefit from the Methylation Panel?

The range of symptoms associated with methylation defects is broad. The Methylation Panel can offer insight in patients with:

  • questionable detoxification (patients who take hormone therapy, drink alcohol, or have toxin exposure)
  • cancer risk
  • cardiovascular disease (non-coronary atherosclerosis, hypertension, coronary artery disease)
  • psychiatric and mood disorders (schizophrenia, autism, bipolar disorder, anxiety, depression)
  • neurologic disorders (Parkinson's disease, cognitive decline)
  • chronic fatigue

 

How are the results of the Methylation Panel helpful?

The Methylation Panel can uncover needs for nutritional support such as amino acids, vitamins, and minerals. Knowing this can help you and your practitioner create personalized dietary and supplement plans.

The Methylation Panel requires a blood draw.

Preparing for this Test

 

Please refer to the instruction included with the collection pack for details on how to perform this collection.

A Personalized Approach to Healthy Aging

The Methylation Panel is an innovative test designed to offer insight into the critical biochemical methylation pathway. Methylation metabolites are measured in plasma, and genetic single nucleotide polymorphisms (SNPs) are analyzed via buccal swab. Patient results are synthesized on a front-page Interpretation-at-a-Glance (IAAG) graphic for quick methylation status assessment. Within the report, results are shown in a methylation pathway graphic to provide a clear understanding of the biochemistry involved.

 

What is Methylation?

Methylation is a chemical process that happens billions of times per second in every cell of the body.1 Methyl groups are transferred and donated between many different molecules which change their structure and function. Methyl groups act like billions of switches which turn genes on or off, help regulate mood, detoxify hormones, produce energy, and promote healthy aging.

Vitamins, minerals, and amino acids from the diet are needed to keep this process running smoothly. There are also genetic factors and oxidative stressors which can affect how well this pathway works.2

 

Why is Methylation important?

  • Methylation is needed to create DNA and RNA and regulate gene expression.
  • It helps make creatine, which is needed for skeletal muscle contraction.
  • Methylation is involved in basic energy production, fat metabolism, immune responses, vascular health, and cell membrane repair.
  • It produces and metabolizes neurotransmitters to regulate mood.
  • Methylation also works to neutralize toxins and hormones.

 

 

Which patients can benefit from the Methylation Panel?

Because of its all-encompassing role in basic human physiology, the range of symptoms associated with methylation defects is broad. The Methylation Panel can offer insight in patients with:

  • questionable detoxification (patients who take hormone therapy, drink alcohol, or have toxin exposure)3,4,5
  • cancer risk6,7,8,9
  • cardiovascular disease (non-coronary atherosclerosis, hypertension, coronary artery disease)10,11,12,13
  • psychiatric and mood disorders (schizophrenia, autism, bipolar disorder, anxiety, depression)6,14,15,16,17
  • neurologic disorders (Parkinson’s disease, cognitive decline)18,19,20
  • chronic fatigue21

 

How are the results of the Methylation Panel helpful?

The Methylation Panel can uncover needs for nutritional support such as amino acids, vitamins, and minerals. Knowing this can help guide dietary and nutraceutical treatment plans. Additionally, knowing genetic predispositions can help focus supplementation to override potential methylation defects.

Optimized Healthy Aging

 

What is methylation anyway?

Methylation is a chemical process that happens in all of the cells in our body billions of times per second – so, pretty important! Methylation relates to mood, detoxification, energy production, and helps the cells age in a healthy way.

 

Which patients can benefit from the Methylation Panel?

The range of symptoms associated with methylation defects is broad. The Methylation Panel can offer insight in patients with:

  • questionable detoxification (patients who take hormone therapy, drink alcohol, or have toxin exposure)
  • cancer risk
  • cardiovascular disease (non-coronary atherosclerosis, hypertension, coronary artery disease)
  • psychiatric and mood disorders (schizophrenia, autism, bipolar disorder, anxiety, depression)
  • neurologic disorders (Parkinson's disease, cognitive decline)
  • chronic fatigue

 

How are the results of the Methylation Panel helpful?

The Methylation Panel can uncover needs for nutritional support such as amino acids, vitamins, and minerals. Knowing this can help you and your practitioner create personalized dietary and supplement plans.

The Methylation Panel requires a blood draw.

Preparing for this Test

 

Please refer to the instruction included with the collection pack for details on how to perform this collection.

How it Works

Consult Doctor

Your doctor will discuss your symptoms and help decide which test is right for you.

Many specimen collections can be completed from the privacy of your home.

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Activate Test

Collection packs can be dropshipped directly to your home and everything you need to begin testing is included.

Already have a collection pack? Activate your test and begin today.

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Collect Samples

Use a calendar to plan for your collection.

Follow instructions carefully and be sure to add important details about you and your specimens in the Activation portal.

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Ship to Lab

Ship your specimens using the prepaid FedEx materials provided.

Results are available online. Schedule time with your physician to review results and create a plan for your health.

FAQ

Review information on the Test Preparation tab above for details on how medications and supplements may impact this test.

We provide a variety of testing services, and some of them may or may not be covered by your insurance plan.

Once your physician has ordered a Genova Diagnostics test for you, you can submit the CPT codes for your test to your commercial insurance plan to determine coverage. For information about billing options, please visit the Billing Information page.

Support guides, charts, and additional aids can be found on the Support Materials tab. Additional educational materials can be found in our Learning Library.

Genova also offers complimentary Medical Education Consultations for healthcare providers. Schedule consults online by signing in to your myGDX account.