Essential Oestrogens FMV/24Hr

Essential Oestrogens™ is a targeted urinary hormone test designed to evaluate oestrogen metabolism specifically. This hormone test offers clinical insight into parent oestrogens, key oestrogen metabolites, and relevant ratios and is useful for initial oestrogen assessment as well as follow-up testing to monitor response to therapies and/or to check levels of previously abnormal results.

Essential Oestrogens® with Genomics

Personalise Patient Treatment Protocols with Genomic Testing

We are excited to announce that the addition of select genomic markers to our Essential Oestrogens profile. Assessment of these select genomic markers (also known as SNPs) in conjunction with urine hormone testing, supports broadened clinical insight into women's and men's health concerns.

Genomic testing using these SNPs may provide awareness into an array of conditions for which the peri/menopausal and andropausal patient seek support such as anxiety and other mood shifts, cardiovascular disease, cardiometabolic syndrome, bone health and hormone detoxification capacity.

Complete Hormones with Genomics

Complete Hormones kit requisitions will now include the option for ordering one or more of the following SNPs:

  • MTHFR – Methylenetetrahydrofolate Reductase
    • Low bone mineral density and/or fracture risk
    • Potential risk of all cancers
    • Low levels of B vitamins, especially folate
    • Risk for cardiovascular disease and stroke

  • COMT – Catechol-O-Methyltransferase
    • Mood Disorders
    • Chronic, high levels of stress
    • Increased risk for fracture
    • High or imbalanced estrogen levels, especially 4-hydroxyestrogn

  • VDR – Vitamin D Receptor
    • Autoimmune diseases
    • Metabolic syndrome
    • Cancer risk and progression
    • Osteopenia/osteoporosis

  • CY1B1 – Cytochrome P450 1B1
    • Increased risk for cancers in specific populations
    • Exposure-specific cancers

Oestrogen imbalance can produce challenging symptoms during the transitional periods of perimenopause/ menopause and andropause (male menopause) including:

  • Weight gain
  • Anxiety
  • Fatigue
  • Low sex drive and performance issues
  • Hair loss
  • Sleep disturbances
  • Mood instability
  • Brain fog
  • Hot flashes

Why use the Essential Oestrogens profile?

In conventional hormone testing, basic parent hormones (oestrogens, progesterone, etc.) are usually measured in blood. However, urinary hormone testing, as offered in Essential Oestrogens, provides several advantages:

  • Urinary hormone testing provides a more comprehensive look at hormone metabolism, measuring basic parent hormones, as well as compounds produced from parent hormones
  • Emerging research reinforces the potential relationship of disease risk with downstream oestrogen metabolites, which are not routinely measured in blood testing and not available in salivary testing
  • Available as a convenient at-home collection of a first-morning or 24-hour specimen

The Essential Oestrogen test is a subpanel of Complete Hormones, a more comprehensive evaluation of sex- and steroid-hormone biomarkers.

Test Type: Urine Test

Analyte List
16 alpha-hydroxyestrone
2 - Hydroxyestrone
2 - Methoxyestrone
2 hydroxy : 16 alpha hydroxy-estrone Ratio
2-Methoxyestrone : 2-Hydroxyestrone Ratio
4 - Hydroxyestrone
4 - Methoxyestrone
Specimen Requirements
1 x urine sample