Menopause Plus™ is a salivary hormone test that examines three specimens for levels of β-estradiol, estrone, estriol, progesterone, and testosterone. In addition to the Menopause test, this hormone test includes the Adrenocortex Stress Profile and the Comprehensive Melatonin Profile to reveal how the sex hormones are influenced by cortisol, DHEA, and melatonin. Results can be used to identify hormone imbalances contributing to menopausal symptoms as well as various systemic disorders. Identification of hormonal imbalances enables the practitioner to customize a hormone replacement therapy (HRT) program.
Following menopause, a marked decrease in estrogen production can result in distinct changes in female physiology. Dramatic reductions in hormone levels or imbalances between estrogen, progesterone, and testosterone can lead to:
- Hot flashes
- Impaired memory
- Altered lipid metabolism
- Accelerated aging of skin
By the time a woman reaches menopause, her total estrogen production has typically declined by 70-80% and her androgen production by 50%. Reduced hormonal levels are associated with increased risk for osteoporosis and cardiovascular disease. In addition, potential functional impairments include:
- Immune regulation
- Mood control
- Glycemic control
- Sex drive
Establishing baseline hormone measurements of estrogens, progesterone, and testosterone is critical in determining the need for hormone replacement therapy (HRT). Hormone levels may be normal, indicating that HRT is not needed. Reference ranges are based on non-supplementing post-menopausal women. Excess levels of estradiol, estrone, or testosterone may signify a higher risk of breast or endometrial cancer.