Neopterin/Biopterin Profile

Products of Tetrahydrobiopterin (BH4)

Neopterin and biopterin are by-products of the redox reactions involving tetrahydrobiopterin (BH4). BH4 functions as a cofactor for the enzymes responsible for the production of monoamine neurotransmitters (ephinepherine, norepinephrine, DOPA, serotonin), and as a cofactor in nitric oxide production.

Neopterin is a marker of inflammation and cellular immune response, allowing detection and monitoring of inflammatory processes.

Neopterin is elevated in:

  • Infections
  • Autoimmune diseases: Rheumatoid Arthritis, Systemic Lupus, and Atopic Asthma
  • Conditions of T-cell or macrophages activation
  • Psychiatric disorders
  • Sleep-disordered breathing
  • Neurological Disease

Neopterin/Biopterin Profile

  • A simple overnight urine specimen; no blood draw is necessary!
  • Order this profile by itself or get a special discount when you order it as an add-on with: Organix Profiles, ION Profiles, Cardio/ION Profile, TRIAD Profile, or Toxic Effects Porphyrins Profile.

Test name(s): 0088 - Neopterin/Biopterin Profile*

Method: LC/MS-MS, Spectrophotometry

*Not available in New York

Test Type: Urine Test

Analyte List
Specimen Requirements