ONE (Optimal Nutritional Evaluation)

ONE FMV nutritional test helps to give an understanding of individual diet and supplementation needs, and offers a personalized functional nutrition assessment covering Antioxidants, B Vitamins, Digestive Support, and Minerals.

Nutritional deficiencies can be a factor of many complex chronic conditions, and ONE FMV utilizes an easy first-morning urine collection (called a first morning void) to provide nutritional recommendations based on a patient’s individual nutritional test results. Clinicians commonly use such nutritional testing to determine the nutritional deficiencies that are at the root of chronic conditions.

Symptoms and chronic conditions related to nutritional deficiencies:

  • Mood disorders
    • Depression
    • Anxiety
    • Sleepdisturbance
  • Fibromyalgia
  • Fatigue
  • Optimized health and sports fitness

Using an easy-to-collect, first-morning urine sample, the ONE FMV nutritional test gives physicians a better understanding of patients’ diet and nutritional deficiencies. By combining testing in 4 key areas of core nutrients, physicians are offered a depth of insight into a patient’s overall nutritional status unrivaled in the laboratory industry. Genova Diagnostics has created an enhanced nutritional test report that synthesizes the results of nearly 80 individual biomarkers into one, easy-to-interpret overview, as well as a personalized patient supplementation schedule.

The ONE FMV Nutritional Test Covers:

  • MetabolicAnalysis Profile: Assessment provides information on 45 key organic acids. These biomarkers are grouped into easy-to-understand categories, and provide insight for functional support in the areas of: malabsorption & dysbiosis; cellularenergy & mitochondrial metabolism; neurotransmitter metabolism; vitamin deficiencies; and toxin exposure & detoxification need.
  • Amino Acids Analysis: Features either plasma (37 total) or urine (41 total) amino acids. This assesses nutritionally essential and non-essential amino acids, as well as intermediary metabolites that augment an understanding of B vitamin need, and need for support of protein digestion & absorption.
  • OxidativeStress: Biomarkers highlight the body’s current state of oxidative stress andreserve capacity. Markers of oxidative injury assess cell membrane (lipidperoxides) and DNA(8-hydroxydeguanosine/8-OHdG) damage, while direct measurement of glutathioneand CoQ10 provide insight into antioxidant reserve available to counterfree-radical impact. Additional markers are available in our Oxidative Stress 2.0 profile.

Test Type: Urine Test

Analyte List
1-methylhistidine
2-Hydroxyphenylacetic Acid
3-Hydroxyisovaleric Acid
3-Hydroxyphenylacetic Acid
3-Hydroxyproprionic Acid
3-Methyl-4-OH-phenylglycol
3-methylhistidine
4-Hydroxyphenylacetic Acid
5-OH-Indoleacetic Acid
8-hydroxy-deoxy Guanosine (8-OHdG)
Adipic Acid
Alanine
Alpha-amino-N-butyric acid
Alpha-aminoadipic acid
Anserine (dipeptide)
Arabinose
Arginine
Asparagine
Aspartic acid
Benzoic Acid
Beta-alanine
Beta-aminoisobutyric acid
Carnosine (dipeptide)
Cis-Aconitic Acid
Citramalic Acid
Citric Acid
Citrulline
Creatinine
Cystathionine
Cysteine
Cystine
Dihydroxyphenylpropionic Acid
Ethanolamine
Formiminoglutamic Acid
Gamma-aminobutyric acid
Glutamic acid
Glutamine
Glutaric Acid
Glycine
Hippuric Acid
Histidine
Homogentisic Acid
Homovanillic Acid
Indoleacetic Acid
Isocitric Acid
Isoleucine
Isovalerylglycine
Kynurenic / Quinolinic Ratio
Kynurenic Acid
Lactic Acid
Leucine
Lipid peroxides - urine
Lysine
Malic Acid
Methionine
Methylmalonic Acid
Ornithine
Orotic Acid
Phenylacetic Acid
Phenylalanine
Phosphoethanolamine
Phosphoserine
Proline
Pyroglutamic Acid
Pyruvic Acid
Quinolinic Acid
Sarcosine
Serine
Suberic Acid
Succinic Acid
Tartaric Acid
Taurine
Threonine
Tryptophan
Tyrosine
Urea
Valine
Vanilmandelic Acid
Xanthurenic Acid
a-Hydroxyisobutyric Acid
a-Keto-b-Methylvaleric Acid
a-Ketoadipic Acid
a-Ketoglutaric Acid
a-Ketoisocaproic Acid
a-Ketoisovaleric Acid
a-Ketophenylacetic Acid
b-OH-Butyric Acid
b-OH-b-Methylglutaric Acid
Specimen Requirements
First morning urine collection - three tubes of 5ml each as per supplied kit.