Clinical Pearls
HPA Axis and The Gut


Michelle Maddux, NDThe HPA axis is the body's stress response system. Acute stress causes the HPA axis to start a systemic hormonal cascade that enables the body to react quickly to the stressor – the "fight or flight" response. In today's world, stress is often chronic, but the HPA axis responds in the same way as it does to acute stress. This results in a repetitive and continuous stress hormone cascade that impacts every system in the body. Patients who experience this constant sympathetic state have a variety of symptoms that can be vague and seemingly unrelated. In this webinar, Dr. Michelle Maddux uses case studies to illustrate how adrenal dysfunction and GI conditions may be related, and discusses how to assess and treat complex patients with GI complaints.


Clinical Pearls

Complex Patient
Approach to Complex Patients

Clinical Pearl 1

When a patient has multiple symptoms in several systems that are fundamental to health, where do you begin to sort it out? In this segment, Dr. Michelle Maddux describes an approach that can be used in complex patients.

Play – Approach to Complex Patients

Common Causes
HPA Axis Function & Dysfunction

Clinical Pearl 2

The Cortisol Awakening Response (CAR) and the cortisol diurnal curve tell us different things about the HPA axis function and dysfunction. Listen as Dr. Michelle Maddux explains the difference between the two patterns and mechanisms, and what they can tell us about underlying problems and root causes.

Play – HPA Axis Function and Dysfunction

Awake
Sample Timing

Clinical Pearl 3

To accurately measure CAR, the timing of sample collection is critical because the response is transient. Here Dr. Michelle Maddux answers the most common questions about sample timing, including the definition of "awake."

Play – Sample Timing

Case Studies: HPA Axis and the Gut

GI complaints, as well as a wide range of symptoms such as fatigue, insomnia, and weight gain, are among the most common conditions practitioners see. Complex patients often require the evaluation of several body systems to determine the root of the problem. Assessment of the HPA axis can be key in understanding the relationship of seemingly unrelated symptoms, including GI complaints.

Join Dr. Michelle Maddux as she uses two case studies to illustrate the relationship between the HPA axis and the gut, and describes the diagnostic and therapeutic approach to patients, in the webinar entitled "Case Studies: HPA Axis and the Gut."

This webinar can be viewed in its entirety on our LIVEGDX webinar archive.

LIVEGDX Webinar Archive