Cardiovascular disease is an inflammatory disease necessitating a multidisciplinary approach. In addition to evaluating standard cardiovascular risk factors (diabetes/insulin resistance, obesity, hypertension, hyperlipidemia and tobacco abuse), other inflammatory etiologies (toxins, infections) need to be considered. Further, genetic variations, called single nucleotide polymorphisms (SNPs), along with environmental factors modulate phenotypic gene expression. The latter can impact the development and progression of cardiovascular disease as well as cardiovascular mortality. Understanding how genetic risk and environmental factors allows clinicians to individualize diagnostic and therapeutic interventions.
- Have a better understanding of some of the common genetic polymorphisms (SNPs) that impact cardiovascular disease
- Review the importance of inflammation in cardiovascular disease
- Using case studies, demonstrate a multidisciplinary approach to addressing cardiovascular risk
Keywords: cardiovascular disease – inflammatory disease – single nucleotide polymorphisms (SNPs)
Doreen Saltiel, MD, FACC
Doreen Saltiel, MD, FACC previously practiced functional medicine and cardiology in St. Louis with a focus on preventive cardiology utilizing advanced functional testing, micronutrient testing and other non-invasive technologies to decrease cardiovascular morbidity and mortality. She also served as Medical Consultant to the Metabolic Medicine Institute (MMI) and Co-Director of Graduate Education, Program in Integrative Medicine, George Washington University School of Medicine and Health Sciences.
Dr. Saltiel practiced interventional cardiology for more than 20 years. She completed her cardiology fellowship at Walter Reed and served 14 years on active duty in the Army, culminating as the Chief of Cardiology at Eisenhower Army Medical Center and the Southeast Region Cardiology Consultant. She also completed advanced fellowship training in Metabolic and Nutritional Medicine from MMI and MMI's advanced certifications in Cardiovascular Health and Endocrinology.
Doreen holds a Medical Degree from New York Medical College and a Juris Doctorate from the University of Missouri-Columbia School of Law.