HPA-Axis Dysfunction in Obesity

Melanie Dorion, AGNP


Obesity is a multifaceted disease and requires a comprehensive approach for successful management. Diet, lifestyle, and insulin/glucose metabolism are commonly the focus of treatment. Often overlooked, however, are other factors in the obese patient's metabolism such as dysfunction in the hypothalamic-pituitary-adrenal (HPA) axis.

Elevated cortisol or abnormal cortisol patterns are often contributing factors in weight gain and/or resistant weight loss and should be addressed early in a treatment plan. This webinar will focus on exploring HPA-axis dysfunction in the obese patient and review treatment options to support successful weight loss.

Learning Objectives

  • Review contributing factors in weight gain
  • Discuss research on HPA-axis dysfunction in obesity
  • Introduce therapeutic options focusing on adrenal support

Keywords: adrenal dysfunction – weight gain – hypothalamic-pituitary-adrenal (HPA) axis

Melanie Dorion, AGNPAviva Romm, MD

Melanie Dorion is an Adult Geriatric Nurse Practitioner focusing on preventive and integrative health in teens and adults. She currently is the Functional Medicine specialist at Downtown Family Healthcare, a family practice in Charlottesville, VA, focusing on fatigue, Lyme disease, weight management, and gastrointestinal health. Her approach is grounded in the Naturopathic philosophy and she studied Naturopathic Medicine at Bastyr University in Washington before doing her Nurse Practitioner degree at Seattle University. She is a member of the Obesity Medicine Association and the Institute for Functional Medicine and has received advanced training in obesity management, nutrition, exercise science, and methylation genetics. She is a former professional cyclist and Quebec Cycling Hall of Fame inductee. Melanie enjoys cycling, running, hiking, cooking, gardening, and spending time with her family.

Genova Diagnostics offers webinar sessions that are designed to answer your most pressing questions about test profiles and popular topics in functional medicine.

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