Methylation is a complex process in which methyl groups (CH3) are transferred or donated between molecules, thereby changing their structure and function. This happens billions of times per second in every cell throughout the body. The methylation cycle is dependent on amino acids, vitamin cofactors, and minerals obtained from the diet to facilitate adequate function of this complex biochemical pathway.
Proper methylation is crucial to an enormous number of systemic biological processes, including creatine production for skeletal muscle contraction, DNA and RNA synthesis, gene regulation (epigenetics), hormone regulation and detoxification, energy production, cell membrane repair, fat metabolism, myelination, and immune function. However, key amino acid deficiencies, lack of vitamin and mineral cofactors, genetic enzymatic predispositions, and a wide array of oxidative stressors can affect each of these pathways and a patient's overall methylation status.
The webinar will introduce the innovative Methylation Panel, offering insight into the critical biochemical methylation pathway. By measuring analytes involved in the methylation cycle, as well as testing genetic predispositions for altered enzymatic activity, this profile can help clinicians design more targeted treatment strategies to optimize patient outcomes.
- Review the methylation and transsulfuration pathways
- Discuss the interpretation and application of laboratory test results
- Apply nutritional and lifestyle therapies to support methylation status
Michael Chapman, ND
Michael Chapman, N.D., is a licensed naturopathic physician who graduated from Bastyr University in Seattle, Washington. Upon graduation, he spent three years in private practice before joining the team at Genova Diagnostics. His areas of clinical focus are hormone regulation, gastrointestinal health, and autonomic balance.
Prior to medical school, Dr. Chapman earned his Bachelor of Science degree from Indiana University with a focus in neuropsychology. He later worked as a microbiologist performing pharmaceutical research on cancer cell lines.